Angel becomes more ill and eventually succumbs to AIDS. At Angel's funeral on Halloween, the group goes their separate ways after a bitter argument, although Maureen and Joanne reconcile in the process ("I'll Cover You/Goodbye Love").

In the final scene, Trelkovsky is bandaged up in the same fashion as Simone Choule, in the same hospital bed. From his perspective, his and Stella's visit to Simone is shown. Trelkovsky then lets out a monstrous scream as Simone did in the earlier scene.